IC 805 is a potent analgesic and anti-inflammatory compound

It harnesses the power of DENKI technology for post-surgical applications, like pain management after cataract surgery. Its sister compound, IC 800, will be used in chronic cases to alleviate neuropathic pain and pain associated with dry eye.

IC 805 offers a number of benefits:

New non-opioid pain management option in the making

Potential for an effective anti‑inflammatory effect

May be more effective than steroids and NSAIDs

Possible decline in abuse and safety concerns associated with opioid drugs

IPAC’s R&D in action

IC 805 uses our proprietary molecule DENKI to inhibit enzymes that degrade the body’s natural response to pain. DENKI can increase the local concentrations of enkephalins, the opioid peptides produced by the body to relieve pain.

IC 805: Development strategy

Scientific and clinical validation

  • Preclinical ocular studies in animals demonstrated that the drug was effective, safe, and well tolerated


  • Complete development of ocular formulation

  • Open Investigational New Drug (IND) application with US FDA

Clinical Development 

  • Open Investigational New Drug (IND) application with US FDA

  • Conduct Phase 1 study, then Phase 2 study, in dry eye patients

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IC 265

for the treatment of dry eye